Exploratory study on sequestration of some essential metals by indigo carmine food dye

Authors

  • Thalita Boldrin Zanoni State University of São Paulo Júlio de Mesquita Filho; Institute of Chemistry
  • Arnaldo Alves Cardoso State University of São Paulo Júlio de Mesquita Filho; Institute of Chemistry
  • Maria Valnice Boldrin Zanoni State University of São Paulo Júlio de Mesquita Filho; Institute of Chemistry
  • Antonio Aparecido Pupim Ferreira State University of São Paulo Júlio de Mesquita Filho; Institute of Chemistry

DOI:

https://doi.org/10.1590/S1984-82502010000400014

Keywords:

Metal sequestration, Indigo carmine, Food dye^i1^scomplexat, Spectrophotometric analysis, Copper^i1^sdeterminat

Abstract

Indigo carmine forms a stable complex with different ions, and the stability constant of the complexes were evaluated as log K equal to 5.75; 5.00; 4.89 and 3.89 for complexes with Cu(II), Ni(II), Co(II) and Zn(II) ions, respectively, in 0.1 mol L-1 carbonate buffer solution at pH 10. The interaction between Cu(II) ions and indigo carmine (IC) in alkaline medium resulted in the formation of the Cu2(IC) complex, measured by the spectrophotometric method, with a stoichiometric ratio between indigo carmine and metal ions of 2:1 (metal-ligand). The reported method has also been successfully tested for determination of copper in pharmaceutical compounds based on copper-gluconate without pre-treatment.

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Published

2010-12-01

Issue

Vol. 46 No. 4 (2010)

Section

Articles

License

All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY.

The on line journal has open and free access.

How to Cite

Exploratory study on sequestration of some essential metals by indigo carmine food dye . (2010). Brazilian Journal of Pharmaceutical Sciences, 46(4), 723-730. https://doi.org/10.1590/S1984-82502010000400014