Oral delivery system for peptides and proteins: II. Application of microencapsulation methods

Authors

  • Catarina Silva Universidade de Coimbra; Faculdade de Farmácia; Laboratório de Tecnologia Farmacêutica
  • António Ribeiro Instituto Superior da Ciências da Saúde do Norte; Laboratório de Tecnologia Farmacêutica
  • Domingos Ferreira Universidade do Porto; Faculdade de Farmácia; Laboratório de Tecnologia Farmacêutica
  • Francisco Veiga Universidade de Coimbra; Faculdade de Farmácia; Laboratório de Tecnologia Farmacêutica

DOI:

https://doi.org/10.1590/S1516-93322003000100002

Keywords:

Microencapsulation, Natural polymers, Oral administration, Peptide drugs

Abstract

Choosing an appropriate microencapsulation method to improve the oral bioavailability of peptide drugs depends on the drug physico-chemical properties, operation conditions and selected polymers. Microencapsulation techniques and its application in peptide and protein oral delivery are reviewed. Natural polymers and techniques involving no harsh conditions such as extreme pH, high temperature and solvents use are the most important when encapsulating peptide drugs.

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Published

2003-03-01

Issue

Vol. 39 No. 1 (2003)

Section

Original Papers

How to Cite

Oral delivery system for peptides and proteins: II. Application of microencapsulation methods. (2003). Revista Brasileira De Ciências Farmacêuticas, 39(1), 1-20. https://doi.org/10.1590/S1516-93322003000100002