Analysis of the mother-to-child transmission rate of HIV and maternal-fetal risk factors in exposed children born in a reference center in the state of Goiás
DOI:
https://doi.org/10.11606/issn.1679-9836.v100i5p449-454Keywords:
HIV, Child, Mother-to-child transmission, EpidemiologyAbstract
Objectives: To estimate the mother-to-child transmission rate of HIV and the maternal-fetal risk factors in children born in 2015 in follow-up during the years 2015 to 2017 in the largest reference center for HIV treatment in the state of Goiás. Methods: Retrospective cohort study of 111 HIV-exposed children born in 2015 of HIV-positive mothers, with 19 follow-up losses. Results: Among the mothers, 85 (92.4%) used ART during pregnancy. Of the 92 children who maintained follow-up, 4 (4.34%) acquired perinatal HIV infection. 81 (88%) newborns used antiretroviral prophylaxis. An important protective factor for vertical HIV transmission was neonatal prophylaxis (OR:0.02, 95%; CI: 0.00-0.56, p = 0.04). Other investigated factors, such as ART during pregnancy, were not statistically significant for risk. Conclusion: The vertical transmission rate of HIV is still high in the State of Goiás and the challenges for its prevention consist in the loss of follow-up and failures in the strategic measures.
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Copyright (c) 2021 Renata Rodrigues Rosa , Maly de Albuquerque , Ricardo Vieira Teles-Filho, Guilherme de Matos Abe , Solomar Martins Marques, Paulo Sérgio Sucasas da Costa
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