Escherichia coli produtora de toxina Shiga resistentes a antimicrobianos isoladas de ovinos
DOI:
https://doi.org/10.11606/issn.1678-4456.bjvras.2022.196807Palavras-chave:
STEC, Antibiótico, Beta-lactamases, Zoonoses, ToxinasResumo
A presença de Escherichia coli produtora de toxina Shiga (STEC) e resistente a beta-lactâmicos em ovinos saudáveis, representa um risco potencial para a saúde pública. O objetivo deste estudo foi caracterizar isolados STEC presentes em fezes de ovinos, quanto a produção de toxina, bem como a resistência aos antibióticos beta-lactâmicos. No presente estudo, dentre os quarenta isolados, foi observada a predominância do subtipo Stx1 (22/40), seguido do subtipo Stx1+ Stx2 (11/40), enquanto o grupo menos prevalente foi Stx2 (7/40). A resistência fenotípica aos antibióticos beta-lactâmicos foi observada em 50% (20/40) das cepas analisadas, formando dois grupos, um com isolados resistentes e outro de isolados não resistentes. A citotoxicidade dos isolados não variou entre os grupos. Alguns isolados multirresistentes, além de possuírem essa característica, produziram quantidades significativas de toxinas. Isto conclui, que os mecanismos de resistencia antimicrobiana, por meio de beta lactamases estão presentes em STEC de ovinos, e que a citotoxicidade desses isolados é variável com relação a esta resistência.
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