Phytochemical study and antiulcerogenic activity of Syngonanthus bisulcatus (Eriocaulaceae)

Authors

  • Roberta Gomes Coelho UNESP; Instituto de Química de Araraquara; Departamento de Química Orgânica
  • Leônia Maria Batista UFPB; CCS; Departamento de Ciências Farmacêuticas
  • Lourdes Campaner dos Santos UNESP; Instituto de Química de Araraquara; Departamento de Química Orgânica
  • Alba Regina Monteiro de Souza Brito UNICAMP; IB; Departamento de Fisiologia e Biofísica
  • Wagner Vilegas UNESP; Instituto de Química de Araraquara; Departamento de Química Orgânica

DOI:

https://doi.org/10.1590/S1516-93322006000300010

Keywords:

Syngonanthus bisulcatus, Antiulcerogenic activity, Flavonoids

Abstract

From the ethanol extract of the capitula and scapes of Syngonanthus bisulcatus (Koern) Ruhland the flavonoids 5-hydroxy-7,4'-dimethoxy-6-C-beta-D-glucopyranosylflavone, isovitexin (5,7,4'-trihydroxy-6-C-beta-D-glucopyranosylflavone), luteolin (5,7,3',4'-tetrahydroxyflavone), lutonarin (5,3',4'-trihydroxy-6-C-7-O-beta-D-glucopyranosylflavone) and 5,6,3',4'-tetrahydroxy-7-O-beta-D-glucopyrade were isolated. The structure of the compounds were characterized by spectroscopic methods, mainly 1D and 2D NMR experiments, as well as ESMS spectrometry. In addition we examined the effect of the ethanol extract of capitulae and scapes in the ulcer model ethanol/HCl-induced gastric mucosal lesions.

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Published

2006-09-01

Issue

Vol. 42 No. 3 (2006)

Section

Original Papers

How to Cite

Phytochemical study and antiulcerogenic activity of Syngonanthus bisulcatus (Eriocaulaceae). (2006). Revista Brasileira De Ciências Farmacêuticas, 42(3), 413-417. https://doi.org/10.1590/S1516-93322006000300010