Blood coagulation in horses employed for the production of the antibotropic serum

Abstract

In this work we have studied the effect on the blood coagulation of 60 mg of B. jararaca poison injected subcutaneously in serum-productor horses. Tests of coagulation time, coagulation time of recalcified plasma, platelet counts, clot retraction, prothrombin time, consumption of prothrombin and thromboplastin generation were carried out with samples collected before the poison innoculation and 2, 24, 96, 144 and 288 hours after it. A difference statistically significant was found only from the test of prothrombin consumption until 24 hours after, which was greater, when compared with the results obtained before the innoculation.