Association between sarcopenia and history of fractures in elderly patients with type 2 diabetes
DOI:
https://doi.org/10.11606/issn.2176-7262.v53i4p389-397Keywords:
Sarcopenia, Diabetes Mellitus, Fractures, BoneAbstract
Objective: Evaluating the prevalence of sarcopenia in elderly patients with diabetes mellitus (DM), verifying their association with a history of fractures and falls. Study model: Observational, cross-sectional, and analytical. Method: The study was conducted at a university hospital in Campina Grande, Paraíba. It included elderly patients (≥60 years) with DM. Those with a diagnosis of osteoporosis were excluded. The predictor criterion for sarcopenia was calf circumference (CC): <33 cm for women and <34 cm for men. Results: The valid sample was 44 patients, all with type 2 diabetes mellitus (DM2). The prevalence of sarcopenia was 20.4%. There was a statistically significant relationship between sarcopenia and history of fractures in low energy traumas (p=0.022). There was no difference between the groups with and without sarcopenia in relation to the history of falls in the last year (p=0.589). There was an association between the use of psychotropic drugs and the occurrence of falls (p=0.001). Most of the findings converged with those already present in the literature. Conclusion: Although CC is not an established method for the diagnosis of sarcopenia, muscle loss indicated by this measure has been associated with a history of fractures in the elderly with DM2, so that this accessible measurement can alert to initiate interventions that can improve the quality of life of the elderly.
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World Health Organization. Integrated care for older people: guidelines on community-level interventions to manage declines in intrinsic capacity. Geneva; 2017. Disponível em: https://apps.who.int/iris/bitstream/handle/10665/258981/9789241550109-eng.pdf.
Miranda GMD, Mendes ACG, Silva ALA. O envelhecimento populacional brasileiro: desafios e consequências sociais atuais e futuras. Rev. bras. geriatr. gerontol. 2016;19(3):507-19. doi: http://dx.doi.org/10.1590/1809-98232016019.150140.
Moraes EN. Atenção à saúde do idoso: aspectos conceituais. Brasília: Organização Pan-Americana da Saúde; 2012. Disponível em: https://apsredes.org/pdf/Saude-do-Idoso-WEB1.pdf.
Oliveira B, Concone MHVB, Lodovici FMM, Lopes RGC, Côrte R. Quem cuidará de nós em 2030? Prospecção e consenso na região metropolitana de São Paulo. Estud. interdiscipl. envelhec. 2016;21(1):11-34. Disponível em: https://seer.ufrgs.br/RevEnvelhecer/article/view/49469/40710.
Yang R, Zhang Y, Shen X, Yan S. Sarcopenia associated with renal function in the patients with type 2 diabetes. Diabetes Res Clin Pract. 2016;118:121-9. doi: https://doi.org/10.1016/j.diabres.2016.06.023
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39(4):412-23. doi: https://doi.org/10.1093/ageing/afq034.
Rosenberg IH. Sarcopenia: Origins and Clinical Relevance. J Nutr. 1997; 127(Supl 7):990S-991S. doi: https://doi.org/10.1093/jn/127.5.990S.
Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. doi: 10.1093/ageing/afy169.
Guglielmi G, Ponti F, Agostini M, Amadori M, Battista G, Bazzocchi A. The role of DXA in sarcopenia. Aging Clin Exp Res. 2016;28(6):1047-60. doi: https://doi.org/10.1007/s40520-016-0589-3.
Pagotto V, Santos KFD, Malaquias SG, Bachion MM, Silveira EA. Calf circumference: clinical validation for evaluation of muscle mass in the elderly. Rev Bras Enferm. 2018;71(2):322-8. doi: https://doi.org/10.1590/0034-7167-2017-0121.
Barbosa-Silva TG, Bielemann RM, Gonzalez MC, Menezes AM. Prevalence of sarcopenia among community-dwelling elderly of a medium-sized South American city: results of the COMO VAI? study. J Cachexia Sarcopenia Muscle. 2016;7(2):136-43. doi: https://doi.org/10.1002/jcsm.12049.
Kramer IF, Snijders T, Smeets JSJ, Leenders M, van Kranenburg J, den Hoed M, et al. Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients. J Gerontol A Biol Sci Med Sci. 2017;72(10):1369-75. doi: https://doi.org/10.1093/gerona/glw253.
Fabrício SCC, Rodrigues RAP, Costa Junior ML. Causas e conseqüências de quedas de idosos atendidos em hospital público. Rev Saude Publica. 2004;38(1):93-99. doi: http://dx.doi.org/10.1590/S0034-89102004000100013.
Bortolon PC, Andrade CLT, Andrade CAF. O perfil das internações do SUS para fratura osteoporótica de fêmur em idosos no Brasil: uma descrição do triênio 2006-2008. Cad Saude Publica. 2011;27(4):733-42. doi: http://dx.doi.org/10.1590/S0102-311X2011000400012.
Stolnicki B, Oliveira LG. Para que a primeira fratura seja a última. Rev Bras Ortop. 2016;51(2):121-26. doi: https://doi.org/10.1016/j.rboe.2016.01.005.
Pérez-López FR, Ara I. Fragility fracture risk and skeletal muscle function. Climacteric. 2016;19(1):37-41. doi: https://doi.org/10.3109/13697137.2015.1115261.
Moon SS. Low skeletal muscle mass is associated with insulin resistance, diabetes, and metabolic syndrome in the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010. Endocr J. 2014;61(1):61-70. doi: https://doi.org/10.1507/endocrj.EJ13-0244.
Kalyani RR, Corriere M, Ferrucci L. Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases. Lancet Diabetes Endocrinol. 2014;2(10):819-29. doi: https://dx.doi.org/10.1016%2FS2213-8587(14)70034-8.
He H, Liu Y, Tian Q, Papasian CJ, Hu T, Deng HW. Relationship of sarcopenia and body composition with osteoporosis. Osteoporos Int. 2016;27(2):473-82. doi: https://doi.org/10.1007/s00198-015-3241-8.
Yu R, Leung J, Woo J. Incremental predictive value of sarcopenia for incident fracture in an elderly Chinese cohort: results from the Osteoporotic Fractures in Men (MrOs) Study. J Am Med Dir Assoc. 2014;15(8):551-8. doi: https://doi.org/10.1016/j.jamda.2014.02.005.
Lipschitz DA. Screening for nutritional status in the elderly. Prim Care. 1944;21(1):55-67.
Santos ADA, Pinho CPS, Nascimento ACS, Costa ACO. Sarcopenia in elderly outpatients: prevalence and associated factors. Nutr Hosp. 2016;33(2):255-62.
Montero-Fernández N, Serra-Rexach JA. Role of exercise on sarcopenia in the elderly. Eur J Phys Rehabil Med. 2013:49(1):131-43.
Hao Q, Hu X, Xie L, Chen J, Jiang J, Dong B, et al. Prevalence of sarcopenia and associated factors in hospitalised older patients: A cross-sectional study. Australas J Ageing. 2018;37(1):62-67. doi: https://doi.org/10.1111/ajag.12492.
Bianchi L, Volpato S. Muscle dysfunction in type 2 diabetes: a major threat to patient’s mobility and independence. Acta Diabetol. 2016;53(6):879-89. doi: https://doi.org/10.1007/s00592-016-0880-y.
Du Y, Wolf IK, KNOPF H. Association of psychotropic drug use with falls among older adults in Germany. Results of the German Health Interview and Examination Survey for Adults 2008-2011 (DEGS1). PLoS One. 2017;12(8):e0182432. doi: https://doi.org/10.1371/journal.pone.0182432.
Sarodnik C, Bours SPG, Schaper NC, van den Bergh JP, van Geel TACM. The risks of sarcopenia, falls and fractures in patients with type 2 diabetes mellitus. Maturitas. 2018;109:70-77. doi: https://doi.org/10.1016/j.maturitas.2017.12.011.
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Copyright (c) 2020 Maria Roseneide dos Santos Torres, Lucian Batista de Oliveira, Marcelo Italiano Peixoto
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