Frequency of osteopenia and osteoporosis in men and women living with HIV/Aids: an observational study
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2021.168968Palabras clave:
HIV, Bone Density, Highly Active Antiretroviral Therapy, Prevalence, DiagnosisResumen
Aims: To identify the frequency in changes of bone metabolism, including below the average value for age, osteopenia, and osteoporosis, in people living with HIV/AIDS (PLWHA) and to compare the frequency of factors associated with bone mineral density (BMD) and body composition between sex. Methods: This observational study assessed 106 PLWHA (65 male) recruited from the University Hospital of Ribeirão Preto Medical School from 2013 to 2014. BMD was measured using Dual Energy X-ray Absorptiometry (DXA). Standard deviation values for Z- and T-score proposed by the International Society for Clinical Densitometry were adopted to classify participants below the average value for age, osteopenia, and osteoporosis. Qui-square and Fischer’s exact tests were employed to compare males and females based on their factors associated with BMD reduction. Results: Fifty-two (49%) PLWHA presented at least one diagnosis for below the average value for age, osteopenia, and osteoporosis, being 37 (57%) and 15 (37%) male and female, respectively. Frequency of alcohol consumption was higher in males (n=20; 30.8%) than females (n=05; 12.2%) (p=0.028). Conclusions: A high rate of PLWHA showed changes in bone metabolism, with a higher frequency in males. The frequency of alcohol consumption was higher in males, and it may partially explain the possible causes of the increased rates of bone metabolism changes observed in this group. This information may help develop strategies for reducing the frequency of diagnosis for below the average value for age, osteopenia, osteoporosis improving quality of life in PLWHA.
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Derechos de autor 2021 Bruno Augusto Aguilar, André Pereira dos Santos, Dalmo Roberto Lopes Machado, Euripedes Bardanulfo Gonçalves Gomide, Emerson Sebastião, Anderson Marliere Navarro
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
