Lack of association between ACE ID genetic polymorphism and diabetes or hypertension in Brazilians aged from 50 to 70 years old

Abstract

The present study examined the association between ACE ID polymorphism and diabetes or hypertension in individuals aged between 50 to 70 years old. The participants were recruited before initiating a physical training program and divided into groups, according to their genotype of the ACE gene; DD (n=40), ID (n=55), or II (n=31). The anthropometrical characteristics of the participants were evaluated and anamneses performed to establish if the participants presented diabetes and/or hypertension. From the data obtained for anthropometric characteristics, diabetes, and hypertension, we did not find any association with the ACE ID genotypes (DD, ID and II). ACE ID polymorphism may not have an association with diabetes or hypertension in the 50 to 70 years old Brazilian population, but it might have an association in other populations with different ages