Evaluation of Triglyceride/HDL-C and Neutrophil/Lymphocyte ratio in the elderly with and without dyslipidemia
DOI:
https://doi.org/10.11606/issn.2176-7262.v53i2p107-114Keywords:
Elderly, Dyslipidemia, Cardiovascular Diseases, Blood Cell Count, BiomarkersAbstract
Introduction: Cardiovascular diseases (CVD) are the leading causes of mortality among the elderly, and dyslipidemia is an important risk factor. Moreover, the Triglyceride/HDL-C and Neutrophils/Lymphocytes ratios are closely related to CVD risk factors. Objective: Comparing the Triglyceride/HDL-C and Neutrophils/Lymphocytes ratios in elderlies’ groups, with and without dyslipidemia. Methods: Documentary, cross-sectional, and retrospective study with a quantitative and comparative approach. The sample was of convenience and included 110 elderlies’ residents in a Long-Term Care for Elderlies. Data on lipid profile, full blood count, age, and sex were obtained and the residents divided into two groups, With Dyslipidemia and Without Dyslipidemia. The Triglyceride/HDL-C and Neutrophils/Lymphocytes ratios for both groups were measured and compared. Results were presented as median and interquartile range and analyzed by the Mann-Whitney test. Categorical variables were represented as absolute (n) and relative (%) frequencies and evaluated by the Chi-square (c2). The statistical program SPSS 20.0® was used with a significance level p < 0,05. Results: Eighty-four elderlies with results of lipid profile and blood count were selected, 56 (67%) were female and 28 (33%) male, with a median age of 75 (69-81) years. The group With Dyslipidemia showed higher values for Triglyceride/HDL-C and Neutrophils/Lymphocytes ratios, there was no statistical difference between the groups studied. Conclusion: The Triglyceride/HDL-C ratio can be used as a preventive measure of cardiovascular diseases in the elderlies’ participants of the study. However, the Neutrophils/Lymphocytes ratio should be interpreted with caution in the elderly, who have particular characteristics regarding the development of cardiovascular diseases.
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